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No organ toxicity, no carcinogenicity signals, no reproductive toxicity have been demonstrated in animal models to date
GHK-Cu is widely used in commercial cosmetic formulations (creams, serums, eye treatments) and has an established presence in the personal care industry under the INCI name Copper Tripeptide-1
Research at the laboratory of M.A.B
In addition, the small leucine-rich repeat proteoglycan of bone extracellular matrix tissue biglycan, which is correlated with an aggressive phenotype of osteosarcoma, supported tumor growth and induced resistance to chemotherapy drug doxorubicin by forming a complex with IGF-1R leading to activation of the IGF-1R signaling pathway in human osteosarcoma cell line MG63 (37)
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