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In addition, iron serves as an essential cofactor for numerous enzymes involved in neurodevelopment and neuronal signaling, including tyrosine hydroxylase and tryptophan hydroxylase involved in dopamine and serotonin synthesis, cytochromes participating in mitochondrial electron transport and energy production, catalase and peroxidases contributing to antioxidant defense, and ribonucleotide reductase required for DNA synthesis and cellular proliferation (Kulaszyska et al
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In the hippocampal CA1 region, VPA-exposed rats showed significant SV depletion compared to controls ( P 0.05 )
Curr Neurol Neurosci Rep 25 , 36 (2025)
