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Researchers should note that PT-141 produces a transient, dose-dependent increase in blood pressure it must not be used by individuals with cardiovascular disease, uncontrolled hypertension, or high cardiovascular risk, and must not be self-administered or used outside a controlled laboratory environment

2020;320(1):E78E86

Research indicates this combination produces robust, pulsatile GH release, making it of significant interest for studies on muscle protein synthesis, fat metabolism, recovery, and age-related GH decline