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Exenatide is the worlds first GLP-RA product
However, when intracellular iron ions are overloaded, Fe 2+ can catalyze the generation of metabolically toxic reactive oxygen species and phospholipid peroxide through the Fenton reaction, leading to cell damage or death (Ingold et al., 2018) (Figure 4)
The clinical recommendation for GLP-1 users is 1.21.5g of protein per kilogram of body weight daily a target that becomes challenging when total caloric intake drops to 1,2001,600 calories per day
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