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Wegovy, in particular, has been approved by the FDA for weight management in mature individuals with obesity or overweight with at least one weight-related condition, such as high blood pressure or type 2 diabetes
Why it was included in the FDA ban In the FDA release, the agency cites a study in which serious adverse events including death occurred when patients were given ipamorelin through an IV
[9] The mechanism appears to involve direct GHS-R1a receptor activation on cardiac cells independent of GH release, since hexarelin (a related GHRP) showed cardioprotective effects even in GH-deficient models
PMID: 33996787
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