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Obesity involves persistent changes to metabolic set points, hunger hormones, and energy regulation that do not reset after weight loss
A long-acting FGF21 alleviates hepatic steatosis and inflammation in a mouse model of non-alcoholic steatohepatitis partly through an FGF21-adiponectin-IL17A pathway
Even with todays best medicines, metabolic surgery offers unique and lasting benefits for people with obesity and diabetes, says Ali Aminian, M.D., director of Cleveland Clinics Bariatric & Metabolic Institute and primary investigator of the study
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