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BP lowering with GLP-1RA is associated with increases in HR by 2-3 beats/minute in large clinical trials and up to 6-10 beats/minute in 24-hour monitoring studies 34 , 45
Doi:10.1056/NEJMoa2404881 Pi-Sunyer X, Astrup A, Fujioka K, et al
However, when combined with other glucose-lowering medicationsparticularly sulfonylureas (e.g., gliclazide) or insulinthe risk of hypoglycaemia increases substantially
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