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Similar concerns apply to phosphodiesterase-5 inhibitors (medications like sildenafil) and L-arginine supplements that also influence nitric oxide signaling
The combination of vitamins B 1, B 6 and B 12 has contraceptive activity, according to recent clinical observations, resulting in substantial analgesic (Klin Wochenschr, 1990, 68: 103-148)
They are grouped as a research convenience, allowing researchers to work with a consistent, standardised composition and reducing variability associated with separate sample preparation in the laboratory
Yet some individuals struggle to absorb enough through diet alone
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