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FABP have broad binding characteristics which includes the ability to bind long-chain (C16C20) fatty acids (LCFA), eicosanoids, bile salts, and peroxisome proliferators
On the skin side, pallor, a yellowish tinge, dryness, hyperpigmented patches (particularly on the hands or face), and mouth or tongue soreness are classic signs
Reclassification to Category 1 would allow 503A pharmacies to compound a substance while it remains under FDA evaluation
If the cause is irreversible then parental therapy should be continued for life
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