The answer depends on whether you're asking about a single schedule adjustment (safe within limits) or a pattern of early dosing (creates cumulative risk)
MD, Age Related Macular Degeneration in Integrative Medicine (Fourth Edition), 2018 Diotallevi M, Checconi P, Palamara AT, Celestino I, Coppo L, Holmgren A, Abbas K, Peyrot F, Mengozzi M, Ghezzi P
The term comes from insulin dosing, where 1 unit of U-100 insulin equals 0.01 mL of U-100 insulin solution
It's important to note that Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide) are FDA-approved for chronic weight management, while Ozempic (semaglutide) and Mounjaro (tirzepatide) are approved for type 2 diabetes management, though sometimes used off-label for weight loss