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For diagnosed deficiency, weekly for 6 to 8 weeks, then biweekly, then monthly maintenance based on follow-up labs

D., & Thalib, L

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After a dose-titration and dose-stable run-in period of up to 16 weeks and a 2-week placebo run-in period, patients with inadequate glycemic control (A1C 7.5% to 10.5%) were randomized to the addition of either 100 mg of Januvia or placebo, administered once daily