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During deep sleep: Growth hormone secretion peaks, driving tissue repair and muscle recovery The brains glymphatic system clears metabolic waste products, including proteins associated with neurodegeneration Cortisol levels reach their daily minimum, allowing the adrenal system to reset Immune function regenerates Cellular repair mechanisms run at maximum efficiency Most adults spend less time in deep sleep than optimal, and this deficit increases with age, stress, alcohol consumption, and certain medications
That, in turn, can lead to further improvements downstream
Presented for research literature review only Brophy PM et al
Additionally, the depletion of intracellular citrulline is crucial for the polarization of proinflammatory macrophages and immune responses (86)
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